Karen Duran

Chromothripsis as a mechanism driving complex de novo structural rearrangements in the germline†

Wigard P. Kloosterman, Victor Guryev, Mark van Roosmalen et al. · Human Molecular Genetics · 2011 · 324 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Mechanisms of Therapy Resistance in Patient-Derived Xenograft Models of BRCA1-Deficient Breast Cancer

Petra ter Brugge, Petra Kristel, Eline van der Burg et al. · JNCI Journal of the National Cancer Institute · 2016 · 208 citations

Medicine, Oncology, Pharmacology +16

Dominant missense mutations in ABCC9 cause Cantú syndrome

Magdaléna Harakaľová, J. J. T. van Harssel, Stef van Lieshout et al. · Nature Genetics · 2012 · 200 citations

Life Sciences, Genetics, Molecular Genetics +9

Constitutional Chromothripsis Rearrangements Involve Clustered Double-Stranded DNA Breaks and Nonhomologous Repair Mechanisms

Wigard P. Kloosterman, Masoumeh Tavakoli‐Yaraki, Markus J. van Roosmalen et al. · Cell Reports · 2012 · 194 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Effectiveness of whole-exome sequencing and costs of the traditional diagnostic trajectory in children with intellectual disability

Glen R. Monroe, G. W. J. Frederix, Sanne M. C. Savelberg et al. · Genetics in Medicine · 2016 · 185 citations · Full text

Life Sciences, Genetics, Pediatrics +16