Qikun Yin

New Disubstituted Quindoline Derivatives Inhibiting Burkitt’s Lymphoma Cell Proliferation by Impeding <i>c-MYC</i> Transcription

Huiyun Liu, Ai-Chun Chen, Qikun Yin et al. · Journal of Medicinal Chemistry · 2017 · 59 citations

New Ligands, Oncogenic Agent, Medicine +10

Design, Synthesis, and Evaluation of New Quinazolinone Derivatives that Inhibit Bloom Syndrome Protein (BLM) Helicase, Trigger DNA Damage at the Telomere Region, and Synergize with PARP Inhibitors

Chenxi Wang, Zi-Lin Zhang, Qikun Yin et al. · Journal of Medicinal Chemistry · 2020 · 46 citations · Full text

Discovery of Isaindigotone Derivatives as Novel Bloom’s Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair

Qikun Yin, Chenxi Wang, Yuqing Wang et al. · Journal of Medicinal Chemistry · 2019 · 44 citations · Full text

Design, Synthesis, and Evaluation of New Selective NM23-H2 Binders as <i>c-MYC</i> Transcription Inhibitors via Disruption of the NM23-H2/G-Quadruplex Interaction

Yuqing Wang, Zhou-Li Huang, Shuo-Bin Chen et al. · Journal of Medicinal Chemistry · 2017 · 42 citations · Full text

Nm23-h2/g-quadruplex Interaction, Molecular Biology, Tumor Biology +17

A small-molecule inhibitor of MDMX suppresses cervical cancer cells via the inhibition of E6-E6AP-p53 axis

Jingwen Zhang, Guohua Yu, Yanting Yang et al. · Pharmacological Research · 2022 · 36 citations · Full text

Cervical Cancer, Medicine, Cervical Cancer Cells +9