Yue-Lei Chen

The design, synthesis and biological evaluations of C-6 or C-7 substituted 2-hydroxyisoquinoline-1,3-diones as inhibitors of hepatitis C virus

Yue-Lei Chen, Jing Tang, Matthew J. Kesler et al. · Bioorganic & Medicinal Chemistry · 2011 · 77 citations

Biochemistry, Hepatitis C Virus, Biological Evaluations +7

Synthesis, biological evaluation and molecular modeling of 2-Hydroxyisoquinoline-1,3-dione analogues as inhibitors of HIV reverse transcriptase associated ribonuclease H and polymerase

Jing Tang, Sanjeev Kumar V. Vernekar, Yue-Lei Chen et al. · European Journal of Medicinal Chemistry · 2017 · 25 citations · Full text

Antiviral Compound, Biochemistry, Medicine +9

C-6 aryl substituted 4-quinolone-3-carboxylic acids as inhibitors of hepatitis C virus

Yue-Lei Chen, Jeana Zacharias, Robert Vince et al. · Bioorganic & Medicinal Chemistry · 2012 · 19 citations

C-6 Aryl, 4-Quinolone-3-carboxylic Acids, Hepatitis C Virus +9

A 2-Hydroxyisoquinoline-1,3-Dione Active-Site RNase H Inhibitor Binds in Multiple Modes to HIV-1 Reverse Transcriptase

Karen A. Kirby, Nataliya Myshakina, Martin T. Christen et al. · Antimicrobial Agents and Chemotherapy · 2017 · 18 citations · Full text