K. Hughes

Modulation of the glycogen synthase kinase-3 family by tyrosine phosphorylation.

K. Hughes, Eleni Nikolakaki, Simon Plyte et al. · The EMBO Journal · 1993 · 620 citations · Full text

Signal Transduction, Molecular Physiology, Biochemistry +10

Differential regulation of glycogen synthase kinase-3 beta by protein kinase C isotypes.

Nigel T. Goode, K. Hughes, James R. Woodgett et al. · Journal of Biological Chemistry · 1992 · 393 citations · Full text

Specific Inactivation, Molecular Regulation, Molecular Biology +17

Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C.

David P. Cook, Michael Fry, K. Hughes et al. · The EMBO Journal · 1996 · 387 citations · Full text

Signal Transduction, Molecular Physiology, Protein Kinase C +12

Identification of multifunctional ATP-citrate lyase kinase as the <i>α</i>-isoform of glycogen synthase kinase-3

K. Hughes, S. Anantha Ramakrishna, James R. Woodgett · Biochemical Journal · 1992 · 115 citations · Full text

Atp-citrate Lyase, Molecular Biology, Molecular Genetics +18

PHF‐tau from Alzheimer's brain comprises four species on SDS‐PAGE which can be mimicked by in vitro phosphorylation of human brain tau by glycogen synthase kinase‐3β

Sandrine Mulot, K. Hughes, James R. Woodgett et al. · FEBS Letters · 1994 · 97 citations · Full text