François Hamy

High Affinity Binding of TAR RNA by the Human Immunodeficiency Virus Type-1 tat Protein Requires Base-pairs in the RNA Stem and Amino Acid Residues Flanking the Basic Region

Mark J. Churcher, C Lamont, François Hamy et al. · Journal of Molecular Biology · 1993 · 286 citations

Life Sciences, Biology, Molecular Biology +11

An inhibitor of the Tat/TAR RNA interaction that effectively suppresses HIV-1 replication

François Hamy, Eduard Felder, Gerhard Heizmann et al. · Proceedings of the National Academy of Sciences · 1997 · 242 citations

Life Sciences, Biochemistry, Molecular Biology +13

A New Class of HIV-1 Tat Antagonist Acting through Tat−TAR Inhibition

François Hamy, Vincent Brondani, Andreas Flörsheimer et al. · Biochemistry · 1998 · 134 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Hydrogen-bonding Contacts in the Major Groove are required for Human Immunodeficiency Virus Type-1 tat Protein Recognition of TAR RNA

François Hamy, Ulysse Asseline, Jane A. Grasby et al. · Journal of Molecular Biology · 1993 · 113 citations

Life Sciences, Biology, Molecular Biology +16

Discovery of novel, highly potent and selective β-hairpin mimetic CXCR4 inhibitors with excellent anti-HIV activity and pharmacokinetic profiles

Steven J. DeMarco, Heiko Henze, Alexander Lederer et al. · Bioorganic & Medicinal Chemistry · 2006 · 86 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11