Ariane J. Brown

Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV

Timothy P. Sheahan, Amy Sims, Sarah R. Leist et al. · Nature Communications · 2020 · 1.8K citations · Full text

Pharmacy, Infectious Diseases, Pharmacotherapy +12

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice

Timothy P. Sheahan, Amy Sims, Shuntai Zhou et al. · Science Translational Medicine · 2020 · 1.2K citations · Full text

Medicine, Infectious Diseases, Pharmacology +17

A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures

Kenneth H. Dinnon, Sarah R. Leist, Alexandra Schäfer et al. · Nature · 2020 · 685 citations · Full text

Veterinary Medicine, Infectious Diseases, Pathobiology +15

A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice

Sarah R. Leist, Kenneth H. Dinnon, Alexandra Schäfer et al. · Cell · 2020 · 671 citations · Full text

Veterinary Medicine, Infectious Diseases, Pathology +11

Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice

Andrea J. Pruijssers, Amelia S. George, Alexandra Schäfer et al. · Cell Reports · 2020 · 540 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17