Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes

M. Baxter, Sarah Withey, Sean Harrison, +18

Journal of Hepatology

Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study

Catherine C. Bell, Anita C. A. Dankers, Volker M. Lauschke, +19

Toxicological Sciences

Tissue EngineeringEngineeringSandwich ConfigurationPathologyCell Culture +18

Three-dimensional perfused human in vitro model of non-alcoholic fatty liver disease

Tomasz Kostrzewski, Terri Cornforth, Sophie Snow, +4

World Journal of Gastroenterology

Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile

James A. Heslop, Cliff Rowe, Joanne Walsh, +13

Archives of Toxicology

Drug DispositionKey FactorsSelective Dedifferentiation ProfileMechanistic EvaluationProteomic Technology +20

Proteome-Wide Analyses of Human Hepatocytes During Differentiation and Dedifferentiation

Cliff Rowe, Dave T. Gerrard, Roz Jenkins, +8

Hepatology

Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans

James Pritchett, Emma Harvey, Varinder Athwal, +13

Hepatology

Polymeric Cups for Cavitation-mediated Delivery of Oncolytic Vaccinia Virus

Rachel Myers, Christian Coviello, Philippe Erbs, +10

Molecular Therapy

Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney

Luke M. Shelton, Adam Lister, Joanne Walsh, +14

Kidney International

Reductive StressTranscriptional RegulationRenal FunctionFunctional GenomicsProteomic Analyses +10

Network Analysis of Primary Hepatocyte Dedifferentiation Using a Shotgun Proteomics Approach

Cliff Rowe, Christopher E. Goldring, Neil R. Kitteringham, +7

Journal of Proteome Research

PathologyNetwork AnalysisSandwich CultureOxidative StressProteomic Technology +23

Role of protein haptenation in triggering maturation events in the dendritic cell surrogate cell line THP-1

Rym Megherbi, Evanthia Kiorpelidou, Brian Foster, +4

Toxicology and Applied Pharmacology

Developmental BiologySignal TransductionCell RegulationImmunologyCellular Biology +7