Naotsuka Okayama

Glucagon-like peptide-1 (GLP-1) protects against methylglyoxal-induced PC12 cell apoptosis through the PI3K/Akt/mTOR/GCLc/redox signaling pathway

Ryosuke Kimura, Masahiro Okouchi, Hiroyuki Fujioka et al. · Neuroscience · 2009 · 128 citations

Life Sciences, Molecular Biology, Pharmacology +14

Expression of zonula occludens and adherens junctional proteins in human venous and arterial endothelial cells: role of occludin in endothelial solute barriers.

Christopher G. Kevil, Naotsuka Okayama, Steven D. Trocha et al. · PubMed · 1998 · 95 citations

Life Sciences, Biochemistry, Cell Biology +14

NRF2-Dependent Glutamate-L-Cysteine Ligase Catalytic Subunit Expression Mediates Insulin Protection Against Hyperglycemia-Induced Brain Endothelial Cell Apoptosis

Masahiro Okouchi, Naotsuka Okayama, J. Steven Alexander et al. · Current Neurovascular Research · 2006 · 95 citations

Life Sciences, Neurobiology, Neuroscience +17

Participation of high glucose concentrations in neutrophil adhesion and surface expression of adhesion molecules on cultured human endothelial cells

Hitoshi Omi, Naotsuka Okayama, Manabu Shimizu et al. · Journal of Diabetes and its Complications · 2002 · 86 citations

Life Sciences, Cell Biology, Immunology +17

Cilostazol inhibits high glucose-mediated endothelial-neutrophil adhesion by decreasing adhesion molecule expression via NO production

Hitoshi Omi, Naotsuka Okayama, Manabu Shimizu et al. · Microvascular Research · 2004 · 81 citations

Life Sciences, Immunology, Pharmacology +12