Sophie Roy

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Publications

Citations

13.5K

H-Index

Active since

1987

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

Merck Canada Inc. (Canada)

McGill University

University of Lausanne

University of British Columbia

Sophie Roy is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in life sciences, caspase activation, and molecular biology.

Publications per year

1987–2022

Publications

A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B

Nancy A. Thornberry, Thomas A. Rano, Erin P. Peterson et al. · Journal of Biological Chemistry · 1997 · 2.1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Involvement of Caspases in Proteolytic Cleavage of Alzheimer’s Amyloid-β Precursor Protein and Amyloidogenic Aβ Peptide Formation

François G. Gervais, Daigen Xu, George S. Robertson et al. · Cell · 1999 · 785 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Cleavage at the Caspase-6 Site Is Required for Neuronal Dysfunction and Degeneration Due to Mutant Huntingtin

Rona K. Graham, Yu Deng, Elizabeth Slow et al. · Cell · 2006 · 649 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +15

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

Vanessa S. Marsden, Liam O’Connor, Lorraine A. O’Reilly et al. · Nature · 2002 · 568 citations

Life Sciences, Cell Biology, Molecular Biology +14

Caspase Cleavage of Gene Products Associated with Triplet Expansion Disorders Generates Truncated Fragments Containing the Polyglutamine Tract

Cheryl L. Wellington, Lisa Ellerby, Abigail S. Hackam et al. · Journal of Biological Chemistry · 1998 · 568 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

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