H Hiai

Quantitative immunohistochemical determination of 8-hydroxy-2'-deoxyguanosine by a monoclonal antibody N45.1: its application to ferric nitrilotriacetate-induced renal carcinogenesis model.

Shinya Toyokuni, Tomoyuki Tanaka, Yuki Hattori et al. · PubMed · 1997 · 584 citations

Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes.

Y Ihara, Shinya Toyokuni, Kôji Uchida et al. · Diabetes · 1999 · 505 citations

Lipid Peroxidation, Insulin Signaling, Redox Biology +17

Cloning and expression of the ret proto-oncogene encoding a tyrosine kinase with two potential transmembrane domains.

Masahide Takahashi, Y Buma, Takashi Iwamoto et al. · PubMed · 1988 · 442 citations

Formation of 4-hydroxy-2-nonenal-modified proteins in the renal proximal tubules of rats treated with a renal carcinogen, ferric nitrilotriacetate.

Shinya Toyokuni, Kôji Uchida, Keigo Okamoto et al. · Proceedings of the National Academy of Sciences · 1994 · 334 citations · Full text

Nitrosative Stress, Lipid Peroxidation, Renal Pathology +23

Overexpression of the rhoC gene correlates with progression of ductal adenocarcinoma of the pancreas

Hirofumi Suwa, Gakuji Ohshio, Takashi Imamura et al. · British Journal of Cancer · 1998 · 274 citations · Full text

Tumor Biology, Pancreatic Cancer, Pathology +7