Charles H. Mitch

The muscarinic M1 agonist xanomeline increases soluble amyloid precursor protein release from chinese hamster ovary-m1 cells

Kris Eckols, Frank P. Bymaster, Charles H. Mitch et al. · Life Sciences · 1995 · 53 citations

Life Sciences, Neuroscience, Pharmacology +11

M1 Receptor Agonist Activity Is Not a Requirement for Muscarinic Antinociception

Malcolm J. Sheardown, H E Shannon, Michael D.B. Swedberg et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 47 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Butylthio[2.2.2] (NNC 11–1053/LY297802): An Orally Active Muscarinic Agonist Analgesic

Michael D.B. Swedberg, Malcolm J. Sheardown, Per Sauerberg et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 32 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Functionally selective M1 muscarinic agonists. 3. Side chain and azacycles contributing to functional muscarinic selectivity among pyrazinylazacycles

John S. Ward, Leander Merrit, David O. Calligaro et al. · Journal of Medicinal Chemistry · 1995 · 29 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Pharmacology of Butylthio[2.2.2] (LY297802/NNC11-1053): A Novel Analgesic with Mixed Muscarinic Receptor Agonist and Antagonist Activity

Harlan E. Shannon, Malcolm J. Sheardown, Frank P. Bymaster et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 26 citations

Medicine, Medicinal Chemistry, Pharmacology +17