Takahiro Onoda

Discovery of a new class of potent, selective, and orally active prostaglandin D2 receptor antagonists

Kazuhiko Torisu, Kaoru Kobayashi, Maki Iwahashi et al. · Bioorganic & Medicinal Chemistry · 2004 · 101 citations

Biochemistry, Functional Selectivity, Medicine +8

Tandem intermolecular alkylation-intramolecular Robinson annelation: A novel and stereoselective construction of the octalin skeleton —Expeditious synthesis of (−)-tanabalin -

Hidenori Watanabe, Takahiro Onoda, Takeshi Kitahara · Tetrahedron Letters · 1999 · 23 citations

Enantioselective Synthesis, Engineering, Molecular Biology +4

Development of prostaglandin D2 receptor antagonist: discovery of highly potent antagonists

Kazuhiko Torisu, Kaoru Kobayashi, Maki Iwahashi et al. · Bioorganic & Medicinal Chemistry · 2004 · 20 citations

Biochemistry, Functional Selectivity, Medicine +10

Discovery of orally active prostaglandin D2 receptor antagonists

Kazuhiko Torisu, Kaoru Kobayashi, Maki Iwahashi et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 17 citations · Full text

Functional Selectivity, Medicine, Immunology +5

3-(2-Aminocarbonylphenyl)propanoic acid analogs as potent and selective EP3 receptor antagonists. Part 2: Optimization of the side chains to improve in vitro and in vivo potencies

Masaki Asada, Maki Iwahashi, Tetsuo Obitsu et al. · Bioorganic & Medicinal Chemistry · 2010 · 14 citations · Full text

Medicinal Chemistry, Biochemistry, Functional Selectivity +11