A J Klein-Szanto

Loss of tuberin in both subependymal giant cell astrocytomas and angiomyolipomas supports a two-hit model for the pathogenesis of tuberous sclerosis tumors.

Elizabeth P. Henske, Lisa L. Wessner, Jeffrey A. Golden et al. · PubMed · 1997 · 159 citations

Medicine, Cell Biology, Oncology +10

The differential expression of N-cadherin and E-cadherin distinguishes pleural mesotheliomas from lung adenocarcinomas

Alejandro Peralta Soler, Karoline Knudsen, Keith R. Johnson et al. · Human Pathology · 1995 · 124 citations

Medicine, Oncology, Pathology +16

Frequent loss of heterozygosity in human primary squamous cell and colon carcinomas at 7q31.1: evidence for a broad range tumor suppressor gene.

Jean C. Zenklusen, Janet C. Thompson, A J Klein-Szanto et al. · PubMed · 1995 · 114 citations

Medicine, Genetics, Molecular Genetics +16

Deletion and mutation analyses of the P16/MTS-1 tumor suppressor gene in human ductal pancreatic cancer reveals a higher frequency of abnormalities in tumor-derived cell lines than in primary ductal adenocarcinomas.

Lingyi Huang, Tamra Goodrow, S Y Zhang et al. · PubMed · 1996 · 86 citations

Medicine, Molecular Genetics, Oncology +17

Expression of p21 is not required for senescence of human fibroblasts.

A.S.C. Medcalf, A J Klein-Szanto, Vincent J. Cristofalo · PubMed · 1996 · 54 citations

Education, Cell Biology, Molecular Biology +16