Martin R. Johnson

Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase.

Dennis Salonga, Kathleen D. Danenberg, Martin R. Johnson et al. · PubMed · 2000 · 834 citations

Medicine, Molecular Biology, Oncology +16

Quantitation of Dihydropyrimidine Dehydrogenase Expression by Real-Time Reverse Transcription Polymerase Chain Reaction

Martin R. Johnson, Kangsheng Wang, Jeffrey B. Smith et al. · Analytical Biochemistry · 2000 · 337 citations

Life Sciences, Biochemistry, Molecular Biology +8

Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA:amino acid N-acyltransferase.

Charles N. Falany, Martin R. Johnson, Stephen Barnes et al. · Journal of Biological Chemistry · 1994 · 240 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Life-threatening toxicity in a dihydropyrimidine dehydrogenase-deficient patient after treatment with topical 5-fluorouracil.

Martin R. Johnson, Alexander Hageboutros, Kangsheng Wang et al. · PubMed · 1999 · 224 citations

Medicine, Oncology, Pharmacology +13

A cancer gene therapy approach utilizing an anti-erbB-2 single-chain antibody-encoding adenovirus (AD21): a phase I trial.

Ronald D. Alvarez, Mack N. Barnes, Jesús Gómez-Navarro et al. · PubMed · 2000 · 161 citations

Medicine, Molecular Medicine, Oncology +17