Martin R. Johnson

Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase.

Dennis Salonga, Kathleen D. Danenberg, Martin R. Johnson et al. · PubMed · 2000 · 833 citations

Pathology, Thymidylate Synthase, Cancer Biology +18

Quantitation of Dihydropyrimidine Dehydrogenase Expression by Real-Time Reverse Transcription Polymerase Chain Reaction

Martin R. Johnson, Kangsheng Wang, Jeffrey B. Smith et al. · Analytical Biochemistry · 2000 · 337 citations

Biochemistry, Natural Sciences, Dna Replication +6

Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA:amino acid N-acyltransferase.

Charles N. Falany, Martin R. Johnson, Stephen Barnes et al. · Journal of Biological Chemistry · 1994 · 236 citations · Full text

Molecular Biology, Taurine Conjugation, Protein Synthesis +18

Life-threatening toxicity in a dihydropyrimidine dehydrogenase-deficient patient after treatment with topical 5-fluorouracil.

Martin R. Johnson, Alexander Hageboutros, Kangsheng Wang et al. · PubMed · 1999 · 224 citations

Oncogenic Agent, Pharmacology, Gt 5 +11

A cancer gene therapy approach utilizing an anti-erbB-2 single-chain antibody-encoding adenovirus (AD21): a phase I trial.

Ronald D. Alvarez, Mack N. Barnes, Jesús Gómez-Navarro et al. · PubMed · 2000 · 161 citations

Gene Therapies, Gene Transfer/expression, Medicine +14