Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses

Daniela Kenzelmann Brož, Stephano S. Mello, Kathryn T. Bieging, +5

Genes & Development

MitophagyGeneticsCell DeathCell CycleAutophagy Genes +19

Desmoglein 1–dependent suppression of EGFR signaling promotes epidermal differentiation and morphogenesis

Spiro Getsios, Cory L. Simpson, Shin-ichiro Kojima, +5

The Journal of Cell Biology

The Differentiation-dependent Desmosomal Cadherin Desmoglein 1 Is a Novel Caspase-3 Target That Regulates Apoptosis in Keratinocytes

Rachel L. Dusek, Spiro Getsios, Feng Chen, +4

Journal of Biological Chemistry

Cell AdhesionApoptosisImmunologyCell DeathCaspase Substrates +17

Coordinated expression of desmoglein 1 and desmocollin 1 regulates intercellular adhesion

Spiro Getsios, Evangeline V. Amargo, Rachel L. Dusek, +4

Differentiation

Signal TransductionRegulates Intercellular AdhesionCell InteractionCell AdhesionDesmoglein 1 +10

Tyrosine-phosphorylated Plakoglobin Is Associated with Desmogleins but Not Desmoplakin after Epidermal Growth Factor Receptor Activation

Claire A. Gaudry, Rachel L. Dusek, Arthur C. Huen, +3

Journal of Biological Chemistry

Loss of the p53/p63 Regulated Desmosomal Protein Perp Promotes Tumorigenesis

Veronica G. Beaudry, Dadi Jiang, Rachel L. Dusek, +6

PLoS Genetics

Efficacy and safety of rucaparib in previously treated, locally advanced or metastatic urothelial carcinoma from a phase 2, open-label trial (ATLAS)

Petros Grivas, Yohann Loriot, Rafael Morales‐Barrera, +19

BMC Cancer

Targeting CD205 with the antibody drug conjugate MEN1309/OBT076 is an active new therapeutic strategy in lymphoma models

Eugenio Gaudio, Chiara Tarantelli, Filippo Spriano, +25

Haematologica

ImmunologyImmunoeditingImmunotherapyTumor BiologyOncology +14

Plakoglobin Deficiency Protects Keratinocytes from Apoptosis

Rachel L. Dusek, Lisa M. Godsel, Feng Chen, +7

Journal of Investigative Dermatology

ApoptosisImmunologyCell DeathDermatologyExperimental Dermatology +3

Targeting CD157 in AML using a novel, Fc-engineered antibody construct

Christina Krupka, Felix S. Lichtenegger, Thomas Köhnke, +14

Oncotarget

Cell TherapyImmunologyNk CellsAntigen ProcessingImmunotherapy +14