Jonathan R. Heyen

Interleukin-6 Facilitates Lipopolysaccharide-Induced Disruption in Working Memory and Expression of Other Proinflammatory Cytokines in Hippocampal Neuronal Cell Layers

Nathan L. Sparkman, Jessica B. Buchanan, Jonathan R. Heyen et al. · Journal of Neuroscience · 2006 · 306 citations · Full text

Immunology, Innate Immunity, Il-6 Deficiency +20

Interleukin (IL)-10 inhibits IL-6 production in microglia by preventing activation of NF-κB

Jonathan R. Heyen, Shi-Ming Ye, Brian N. Finck et al. · Molecular Brain Research · 2000 · 144 citations

Inflammation, Cytokine, Medicine +8

Dual checkpoint blockade of CD47 and PD-L1 using an affinity-tuned bispecific antibody maximizes antitumor immunity

Shih-Hsun Chen, Pawel K. Dominik, Jessica Stanfield et al. · Journal for ImmunoTherapy of Cancer · 2021 · 133 citations · Full text

Structural, functional, and molecular characterization of the SHHF model of heart failure

Jonathan R. Heyen, Eileen Blasi, Kristen J. Nikula et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2002 · 105 citations

Cardiac Muscle, Heart Failure, Engineering +21

Pan-FGFR Inhibition Leads to Blockade of FGF23 Signaling, Soft Tissue Mineralization, and Cardiovascular Dysfunction

Gina M. Yanochko, Allison Vitsky, Jonathan R. Heyen et al. · Toxicological Sciences · 2013 · 70 citations

Angiogenesis, Bone Morphogenic Protein, Pan-fgfr Inhibition Leads +22