Jian Tang

MM-141, an IGF-IR– and ErbB3-Directed Bispecific Antibody, Overcomes Network Adaptations That Limit Activity of IGF-IR Inhibitors

Jonathan B. Fitzgerald, Bryan W. Johnson, Jason Baum et al. · Molecular Cancer Therapeutics · 2013 · 102 citations

Immunology, Tumor Biology, Insulin-like Growth Factor +17

Antibody-mediated targeting of TNFR2 activates CD8 ⁺ T cells in mice and promotes antitumor immunity

Eric M. Tam, Ross B. Fulton, James F. Sampson et al. · Science Translational Medicine · 2019 · 56 citations · Full text

CXCL9 chemokine promotes the progression of human pancreatic adenocarcinoma through STAT3-dependent cytotoxic T lymphocyte suppression

Huifeng Gao, Chien‐shan Cheng, Jian Tang et al. · Aging · 2020 · 36 citations · Full text

<p>Paeonol Inhibits Pancreatic Cancer Cell Migration and Invasion Through the Inhibition of TGF-β1/Smad Signaling and Epithelial-Mesenchymal-Transition</p>

Chien‐shan Cheng, Jingxian Chen, Jian Tang et al. · Cancer Management and Research · 2020 · 35 citations · Full text

Rapid optimization and prototyping for therapeutic antibody-like molecules

Lihui Xu, Neeraj Kohli, Rachel Rennard et al. · mAbs · 2013 · 27 citations · Full text

Rapid Optimization, Systems Biology, Engineering +15