Richard H. Wade

S-Trityl-L-cysteine Is a Reversible, Tight Binding Inhibitor of the Human Kinesin Eg5 That Specifically Blocks Mitotic Progression

Dimitrios A. Skoufias, Salvatore DeBonis, Yasmina Saoudi et al. · Journal of Biological Chemistry · 2006 · 289 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11

Structural changes accompanying GTP hydrolysis in microtubules: information from a slowly hydrolyzable analogue guanylyl-(alpha,beta)-methylene-diphosphonate.

Anthony A. Hyman, Denis Chrétien, Isabelle Arnal et al. · The Journal of Cell Biology · 1995 · 256 citations · Full text

Life Sciences, Biochemistry, Biophysics +16

How does taxol stabilize microtubules?

Isabelle Arnal, Richard H. Wade · Current Biology · 1995 · 241 citations · Full text

Life Sciences, Biochemistry, Cell Biology +7

<i>In vitro</i>screening for inhibitors of the human mitotic kinesin Eg5 with antimitotic and antitumor activities

Salvatore DeBonis, Dimitrios A. Skoufias, Luc Lebeau et al. · Molecular Cancer Therapeutics · 2004 · 218 citations · Full text

Life Sciences, Cell Biology, Pharmacology +17

Interaction of the Mitotic Inhibitor Monastrol with Human Kinesin Eg5

Salvatore DeBonis, Jean‐Pierre Simorre, Isabelle Crevel et al. · Biochemistry · 2002 · 179 citations

Life Sciences, Cell Biology, Molecular Biology +17