Cheng-Kon Shih

Inhibition of HIV-1 Replication by a Nonnucleoside Reverse Transcriptase Inhibitor

Vincent J. Merluzzi, Karl D. Hargrave, Mark E. Labadia et al. · Science · 1990 · 745 citations

Trifluoromethyl group as a pharmacophore: Effect of replacing a CF3 group on binding and agonist activity of a glucocorticoid receptor ligand

Raj Betageri, Yan Zhang, Renée Zindell et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 106 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +7

Novel Non-Nucleoside Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase. 6. 2-Indol-3-yl- and 2-Azaindol-3-yl- dipyridodiazepinones

Terence A. Kelly, Daniel W. McNeil, Janice Rose et al. · Journal of Medicinal Chemistry · 1997 · 51 citations · Full text

Non-nucleoside Inhibitor, Medicine, Human Retrovirus +14

Steady state kinetics and inhibition of HIV-1 reverse transcriptase by a non-nucleoside dipyridodiazepinone, BI-RG-587, using a heteropolymeric template

Elizabeth B. Kopp, John Miglietta, Anthony Shrutkowski et al. · Nucleic Acids Research · 1991 · 50 citations · Full text

Viral Replication, Steady State Kinetics, Molecular Biology +16

Discovery of Imigliptin, a Novel Selective DPP-4 Inhibitor for the Treatment of Type 2 Diabetes

Chutian Shu, Ge Hu, Michael Song et al. · ACS Medicinal Chemistry Letters · 2014 · 39 citations · Full text

Drug Target, Pharmacotherapy, Chemical Biology +16