Christine Brown

The mutational spectrum of type 1 von Willebrand disease: results from a Canadian cohort study

Paula D. James, Colleen Notley, Carol Hegadorn et al. · Blood · 2006 · 351 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Comparative pharmacokinetics of two extended half‐life FVIII concentrates (Eloctate and Adynovate) in adolescents with hemophilia A: Is there a difference?

Manuel Carção, Pierre Chelle, Emily Clarke et al. · Journal of Thrombosis and Haemostasis · 2019 · 48 citations · Full text

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +10

Genetic determinants of VWF clearance and FVIII binding modify FVIII pharmacokinetics in pediatric hemophilia A patients

Laura L. Swystun, Kenichi Ogiwara, Orla Rawley et al. · Blood · 2019 · 47 citations · Full text

Medicine, Hematology, Pharmacokinetics +14

Functional characterization of a 13-bp deletion (c.-1522_-1510del13) in the promoter of the von Willebrand factor gene in type 1 von Willebrand disease

Maha Othman, Yvette Chirinian, Christine Brown et al. · Blood · 2010 · 36 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Analysis of the role of von Willebrand factor, platelet glycoprotein VI-, and α2β1-mediated collagen binding in thrombus formation

Yasuaki Shida, Natalia Rydz, David Stegner et al. · Blood · 2014 · 31 citations · Full text

Medicine, Cell Biology, Hematology +17