J. Van Sande

The human thyrotropin receptor: a heptahelical receptor capable of stimulating members of all four G protein families.

Karl‐Ludwig Laugwitz, Anouk Allgeier, Stefan Offermanns et al. · Proceedings of the National Academy of Sciences · 1996 · 318 citations

Life Sciences, Biochemistry, Endocrinology +16

Somatic mutations causing constitutive activity of the thyrotropin receptor are the major cause of hyperfunctioning thyroid adenomas: identification of additional mutations activating both the cyclic adenosine 3',5'-monophosphate and inositol phosphate-Ca2+ cascades.

Jasmine Parma, J. Van Sande, S. Swillens et al. · Molecular Endocrinology · 1995 · 235 citations · Full text

Medicine, Endocrinology, Genetics +17

The human thyrotropin receptor activates G-proteins Gs and Gq/11.

Anouk Allgeier, Stefan Offermanns, J. Van Sande et al. · Journal of Biological Chemistry · 1994 · 194 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

Thyrotropin activates both the cyclic AMP and the PIP2casades in CHO cells expressing the human cDNA of TSH receptor

J. Van Sande, Eric Raspé, Jason Perret et al. · Molecular and Cellular Endocrinology · 1990 · 188 citations

Life Sciences, Endocrinology, Molecular Biology +6

Dual activation by thyrotropin of the phospholipase C and cyclic AMP cascades in human thyroid

Éric Laurent, Jean Mockel, J. Van Sande et al. · Molecular and Cellular Endocrinology · 1987 · 179 citations

Life Sciences, Endocrinology, Physiology +15