Peter F. Searle

A 12-base-pair DNA motif that is repeated several times in metallothionein gene promoters confers metal regulation to a heterologous gene.

Gary W. Stuart, Peter F. Searle, H Y Chen et al. · Proceedings of the National Academy of Sciences · 1984 · 405 citations · Full text

Molecular Regulation, Genetics, Molecular Biology +21

Identification of multiple metal regulatory elements in mouse metallothionein-I promoter by assaying synthetic sequences

Gary W. Stuart, Peter F. Searle, Richard D. Palmiter · Nature · 1985 · 358 citations

Synthetic Sequences, Systems Biology, Biochemistry +9

Regulation, linkage, and sequence of mouse metallothionein I and II genes.

Peter F. Searle, Barry L. Davison, Gary W. Stuart et al. · Molecular and Cellular Biology · 1984 · 335 citations

Genetics, Genomic Mechanism, Molecular Genetics +17

Structural and Mechanistic Studies of Escherichia coli Nitroreductase with the Antibiotic Nitrofurazone

Paul R. Race, Andrew L. Lovering, Richard M. Green et al. · Journal of Biological Chemistry · 2005 · 213 citations · Full text

Building a metal-responsive promoter with synthetic regulatory elements.

Peter F. Searle, Gary W. Stuart, R D Palmiter · Molecular and Cellular Biology · 1985 · 197 citations · Full text

Engineering, Genetics, Molecular Biology +17