Extensive antigenic diversity among human parainfluenza type 2 virus isolates and immunological relationships among paramyxoviruses revealed by monoclonal antibodies

Masato Tsurudome, Machiko Nishio, Hiroshi Komada, +2

Virology

VaccinationViral EvolutionMolecular VirologyViral PathogenesisImmunology +5

Molecular characterization of fusion regulatory protein-1 (FRP-1) that induces multinucleated giant cell formation of monocytes and HIV gp160-mediated cell fusion. FRP-1 and 4F2/CD98 are identical molecules

Shinji Ohgimoto, Nobutada Tabata, Shigeru Suga, +7

The Journal of Immunology

Recovery of Infectious Human Parainfluenza Type 2 Virus from cDNA Clones and Properties of the Defective Virus without V-Specific Cysteine-Rich Domain

Mitsuo Kawano, Masahiko Kaito, Yuji Kozuka, +7

Virology

Virus StructureViral ReplicationMolecular VirologyV-specific Cysteine-rich DomainDefective Virus +6

The targeted disruption of the CD98 gene results in embryonic lethality

Hideki Tsumura, Noboru Suzuki, Hiromitsu Saito, +6

Biochemical and Biophysical Research Communications

Off-target EffectDevelopmental BiologyCd98 Gene ResultsEmbryonic LethalityGenetics +7

High Resistance of Human Parainfluenza Type 2 Virus Protein-Expressing Cells to the Antiviral and Anti-Cell Proliferative Activities of Alpha/Beta Interferons: Cysteine-Rich V-Specific Domain Is Required for High Resistance to the Interferons

Machiko Nishio, Masato Tsurudome, Morihiro Ito, +3

Journal of Virology

Molecular and biological characterization of fusion regulatory proteins (FRPs): anti-FRP mAbs induced HIV-mediated cell fusion via an integrin system.

Hirofumi Ohta, Masato Tsurudome, Haruo Matsumura, +7

The EMBO Journal

Molecular ImmunologySignal TransductionCell SignalingIntegrin SystemHuman Retrovirus +11

Expression of fusion regulatory proteins (FRPs) on human peripheral blood monocytes. Induction of homotypic cell aggregation and formation of multinucleated giant cells by anti-FRP-1 monoclonal antibodies.

Nobutada Tabata, Masaki Ito, Kaoru Shimokata, +7

The Journal of Immunology

InflammationCytokineAnti-frp-1 Monoclonal AntibodiesHomotypic Cell AggregationImmunology +13

Sequence determination of the hemagglutinin-neuraminidase (HN) gene of human parainfluenza type 2 virus and the construction of a phylogenetic tree for HN proteins of all the paramyxoviruses that are infectious to humans

Mitsuo Kawano, Hisanori Bando, Tetsuya Yuasa, +5

Virology

Viral EvolutionMolecular VirologySequence DeterminationPathogenesisPhylogenetic Tree +7

Fusion regulation proteins on the cell surface: isolation and characterization of monoclonal antibodies which enhance giant polykaryocyte formation in Newcastle disease virus-infected cell lines of human origin

Yasuhiko Ito, Hiroshi Komada, Shigeru Kusagawa, +5

Journal of Virology

Viral ReplicationViral PathogenesisImmunologyPathologyViral Structural Protein +14

Cytological properties of stromal cells derived from giant cell tumor of bone (GCTSC) which can induce osteoclast formation of human blood monocytes without cell to cell contact

Makoto Nishimura, Kimitaka Yuasa, Kouki Mori, +8

Journal of Orthopaedic Research®

Stromal CellsSclerostinImmunologyPathologyCell Proliferation +14