Andrew F. Kyle

Synthesis of macrocyclic natural products by catalyst-controlled stereoselective ring-closing metathesis

Miao Yu, Chenbo Wang, Andrew F. Kyle et al. · Nature · 2011 · 229 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +13

Targeted clearance of senescent cells using an antibody-drug conjugate against a specific membrane marker

Marta Poblocka, Akang Leonard Bassey, Victoria M. Smith et al. · Scientific Reports · 2021 · 129 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17

In Vitro and In Vivo Evaluation of Cysteine Rebridged Trastuzumab–MMAE Antibody Drug Conjugates with Defined Drug-to-Antibody Ratios

Penny Bryant, Martin Pabst, George Badescu et al. · Molecular Pharmaceutics · 2015 · 122 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Efficient and Selective Formation of Macrocyclic Disubstituted <i>Z</i> Alkenes by Ring‐Closing Metathesis (RCM) Reactions Catalyzed by Mo‐ or W‐Based Monoaryloxide Pyrrolide (MAP) Complexes: Applications to Total Syntheses of Epilachnene, Yuzu Lactone, Ambrettolide, Epothilone C, and Nakadomarin A

Chenbo Wang, Miao Yu, Andrew F. Kyle et al. · Chemistry - A European Journal · 2013 · 116 citations

Natural Sciences, Chemistry, Medicinal Chemistry +17

Total synthesis of (−)-nakadomarin A

Andrew F. Kyle, Pavol Jakubec, D.M. Cockfield et al. · Chemical Communications · 2011 · 84 citations

Pharmacy, Chemistry, Medicinal Chemistry +13