Qiyu Qiu

The Combi-Targeting Concept:  Synthesis of Stable Nitrosoureas Designed to Inhibit the Epidermal Growth Factor Receptor (EGFR)

Juozas Domarkas, Fabienne Dudouit, Christopher Williams et al. · Journal of Medicinal Chemistry · 2006 · 70 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Novel Nitrogen Mustard-Armed Combi-Molecules for the Selective Targeting of Epidermal Growth Factor Receptor Overexperessing Solid Tumors:  Discovery of an Unusual Structure−Activity Relationship

Zakaria Rachid, Fouad Brahimi, Qiyu Qiu et al. · Journal of Medicinal Chemistry · 2007 · 49 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

The combi-targeting concept: a novel 3,3-disubstituted nitrosourea with EGFR tyrosine kinase inhibitory properties

Qiyu Qiu, Fabienne Dudouit, Stephanie L. Matheson et al. · Cancer Chemotherapy and Pharmacology · 2003 · 29 citations

Medicine, Medicinal Chemistry, Oncology +13

Multiple mechanisms of action of ZR2002 in human breast cancer cells: A novel combi‐molecule designed to block signaling mediated by the ERB family of oncogenes and to damage genomic DNA

Fouad Brahimi, Zakaria Rachid, Qiyu Qiu et al. · International Journal of Cancer · 2004 · 29 citations

Medicine, Oncology, Pharmacology +15

The Combi-Targeting Concept: <i>In vitro</i> and <i>In vivo</i> Fragmentation of a Stable Combi-Nitrosourea Engineered to Interact with the Epidermal Growth Factor Receptor while Remaining DNA Reactive

Qiyu Qiu, Juozas Domarkas, Ranjita Banerjee et al. · Clinical Cancer Research · 2007 · 24 citations

Medicine, Oncology, Pharmacology +17