G. S. Harris

Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride:  Enzyme-Catalyzed Formation of NADP−Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor

Herbert G. Bull, Margarita García‐Calvo, Stefan Andersson et al. · Journal of the American Chemical Society · 1996 · 157 citations

Life Sciences, Medicinal Chemistry, Pharmacology +17

Inhibition of rat α-reductases by finasteride: Evidence for isozyme differences in the mechanism of inhibition

B. Azzolina, Kenneth Ellsworth, S Andersson et al. · The Journal of Steroid Biochemistry and Molecular Biology · 1997 · 105 citations

Life Sciences, Biochemistry, Pharmacology +11

Effects of finasteride, a type 2 5-alpha reductase inhibitor, on fetal development in the rhesus monkey (Macaca mulatta)

S. Prahalada, A. F. Tarantal, G. S. Harris et al. · Teratology · 1997 · 76 citations

Medicine, Biochemistry, Endocrinology +17

4,7.beta.-Dimethyl-4-azacholestan-3-one (MK-386) and Related 4-Azasteroids as Selective Inhibitors of Human Type 1 5.alpha.-Reductase

Raman K. Bakshi, Gool F. Patel, Gary H. Rasmusson et al. · Journal of Medicinal Chemistry · 1994 · 45 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +7

4-Aza-3-oxo-5.alpha.-androst-1-ene-17.beta.-N-arylcarboxamides as Dual Inhibitors of Human Type 1 and Type 2 Steroid 5.alpha.-Reductases. Dramatic Effect of N-Aryl Substituents on Type 1 and Type 2 5.alpha.-Reductase Inhibitory Potency

Raman K. Bakshi, Gary H. Rasmusson, Gool F. Patel et al. · Journal of Medicinal Chemistry · 1995 · 37 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +6