Patricia Sheppard

Characterization of two cis-acting DNA elements involved in the androgen regulation of the probasin gene.

Paul S. Rennie, Nicholas Bruchovsky, Kevin J. Leco et al. · Molecular Endocrinology · 1993 · 321 citations · Full text

Life Sciences, Endocrinology, Genetics +15

The rat probasin gene promoter directs hormonally and developmentally regulated expression of a heterologous gene specifically to the prostate in transgenic mice.

N M Greenberg, Francesco J. DeMayo, Patricia Sheppard et al. · Molecular Endocrinology · 1994 · 259 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

Development, progression, and androgen-dependence of prostate tumors in probasin-large T antigen transgenic mice: a model for prostate cancer.

Siegfried Kasper, Patricia Sheppard, Y. Yan et al. · PubMed · 1998 · 236 citations

Medicine, Endocrinology, Oncology +12

Cooperative binding of androgen receptors to two DNA sequences is required for androgen induction of the probasin gene.

Siegfried Kasper, Paul S. Rennie, Nicholas Bruchovsky et al. · Journal of Biological Chemistry · 1994 · 143 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Insulin-Like Growth Factor (IGF) Binding Protein-3 Attenuates Prostate Tumor Growth by IGF-Dependent and IGF-Independent Mechanisms

Josef V. Silha, Patricia Sheppard, Suresh Mishra et al. · Endocrinology · 2006 · 95 citations · Full text

Medicine, Cancer Biology, Oncology +11