T. Brennan

Inhibition of alpha-glucosidase I of the glycoprotein-processing enzymes by 6-O-butanoyl castanospermine (MDL 28,574) and its consequences in human immunodeficiency virus-infected T cells

D.L. Taylor, M.S. Kang, T. Brennan et al. · Antimicrobial Agents and Chemotherapy · 1994 · 47 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

The inhibition of human immunodeficiency virus type 1 in vitro by a non-nucleoside reverse transcriptase inhibitor MKC-442, alone and in combination with other anti-HIV compounds

T. Brennan, David Taylor, C G Bridges et al. · Antiviral Research · 1995 · 43 citations

Life Sciences, Molecular Biology, Pharmacology +14

The prevention of cell adhesion and the cell-to-cell spread of HIV-1 in vitro by the α-glucosidase 1 inhibitor, 6-O-butanoyl castanospermine (MDL 28574)

C G Bridges, T. Brennan, Debra L. Taylor et al. · Antiviral Research · 1994 · 32 citations

Life Sciences, Infectious Diseases, Molecular Biology +11

Beneficial replacement of the P1 phenylalanine side chain in HIV-1 protease inhibitors of the difluorostatone type

Daniel Schirlin, V. Van Dorsselaer, Céline Tarnus et al. · Bioorganic & Medicinal Chemistry Letters · 1994 · 13 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Synergistic Inhibition of Human Immunodeficiency Virus Type 1<i>in vitro</i>by 6-0-butanoylcastanospermine (MDL 28574) in Combination with Inhibitors of the Virus-Encoded Reverse Transcriptase and Proteinase

D.L. Taylor, T. Brennan, C G Bridges et al. · Antiviral chemistry & chemotherapy · 1995 · 12 citations

Medicine, Medicinal Chemistry, Pharmacology +17