J C Kraft

Teratogenicity and placental transfer of All-trans-, 13-cis-, 4-oxo-all-trans-, and 4-oxo-13-cis-retinoic acid after administration of a low oral dose during organogenesis in mice

J C Kraft, Boël Löfberg, Ibrahim Chahoud et al. · Toxicology and Applied Pharmacology · 1989 · 114 citations

Pharmacy, Obstetrics, Toxicology +14

The retinoid X receptor ligand, 9-cis-retinoic acid, is a potential regulator of early Xenopus development.

J C Kraft, Timothy J. Schuh, Mont R. Juchau et al. · Proceedings of the National Academy of Sciences · 1994 · 105 citations · Full text

Life Sciences, Developmental Biology, Genetics +17

Low teratogenicity of 13-cis-retinoic acid (isotretinoin) in the mouse corresponds to low embryo concentrations during organogenesis: Comparison to the all-trans isomer

J C Kraft, D. M. Kochhar, William J. Scott et al. · Toxicology and Applied Pharmacology · 1987 · 94 citations

Life Sciences, Developmental Biology, Pharmacology +12

Plasma pharmacokinetics and metabolism of 13-cis- and all-trans-retinoic acid in the cynomolgus monkey and the identification of 13-cis- and all-trans-retinoyl-beta-glucuronides. A comparison to one human case study with isotretinoin.

J C Kraft, William Slikker, J. Bailey et al. · Drug Metabolism and Disposition · 1991 · 65 citations

Medicine, Pharmacokinetics, Pharmacology +16

Influence of 13-cis and all- trans retinoic acid on rat embryonic development in vitro: correlation with isomerisation and drug transfer to the embryo

Stephan Klug, J C Kraft, E. Wildi et al. · Archives of Toxicology · 1989 · 47 citations

Life Sciences, Developmental Biology, Pharmacology +13