Junichi Azuma

Treatment of rheumatoid arthritis with humanized anti–interleukin‐6 receptor antibody: A multicenter, double‐blind, placebo‐controlled trial

Norihiro Nishimoto, Kazuyuki Yoshizaki, Nobuyuki Miyasaka et al. · Arthritis & Rheumatism · 2004 · 789 citations

A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn’s disease☆

Hiroaki Ito, Masakazu Takazoe, Yoshihiro Fukuda et al. · Gastroenterology · 2004 · 635 citations

Inflammation, Chronic Inflammatory Diseases, Allergy +8

Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy

Norihiro Nishimoto, Nobuyuki Miyasaka, Kazuhiko Yamamoto et al. · Modern Rheumatology · 2008 · 335 citations · Full text

Immunology, Pharmacotherapy, Dose Mtx +20

Hypoxic Stress Induces Cardiac Myocyte–Derived Interleukin-6

Keiko Yamauchi‐Takihara, Yoshiji Ihara, Atsushi Ogata et al. · Circulation · 1995 · 299 citations

Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy

Norihiro Nishimoto, Nobuyuki Miyasaka, Kazuhiko Yamamoto et al. · Modern Rheumatology · 2009 · 270 citations · Full text

Immunology, Pharmacotherapy, Dose Mtx +20