Dimitris Gazgalis

On the mechanism of GIRK2 channel gating by phosphatidylinositol bisphosphate, sodium, and the Gβγ dimer

Dailin Li, Taihao Jin, Dimitris Gazgalis et al. · Journal of Biological Chemistry · 2019 · 40 citations · Full text

The small molecule GAT1508 activates brain-specific GIRK1/2 channel heteromers and facilitates conditioned fear extinction in rodents

Yu Xu, Lucas Cantwell, Andrei I. Molosh et al. · Journal of Biological Chemistry · 2020 · 28 citations · Full text

Activating Point Mutations in the <i>MET</i> Kinase Domain Represent a Unique Molecular Subset of Lung Cancer and Other Malignancies Targetable with MET Inhibitors

Federica Pecci, Seshiru Nakazawa, Biagio Ricciuti et al. · Cancer Discovery · 2024 · 23 citations · Full text

A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C. elegans ALS model

Youngwoo Nam, Saba Baskoylu, Dimitris Gazgalis et al. · Scientific Reports · 2018 · 16 citations · Full text

Protein Binding Pocket Optimization for Virtual High-Throughput Screening (vHTS) Drug Discovery

Dimitris Gazgalis, Mehreen Zaka, Bilal Haider Abbasi et al. · ACS Omega · 2020 · 16 citations · Full text

Virtual Screening, Hit Identification, Drug Target +15