J.B. Pracyk

Brain tumors in mice are susceptible to blockade of epidermal growth factor receptor (EGFR) with the oral, specific, EGFR-tyrosine kinase inhibitor ZD1839 (iressa).

Amy B. Heimberger, Chris A. Learn, Gary E. Archer et al. · PubMed · 2002 · 169 citations

Medicine, Oncology, Pharmacology +17

A requirement for the rac1 GTPase in the signal transduction pathway leading to cardiac myocyte hypertrophy.

J.B. Pracyk, K Tanaka, Donald D. Hegland et al. · Journal of Clinical Investigation · 1998 · 148 citations · Full text

Life Sciences, Cardiology, Molecular Biology +13

Protection from reoxygenation injury by inhibition of rac1.

Kyo Sang Kim, Kazuyo Takeda, R Sethi et al. · Journal of Clinical Investigation · 1998 · 145 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

A Randomized Trial of Vascular Hemostasis Techniques to Reduce Femoral Vascular Complications After Coronary Intervention 11This study was designed, supported, and internally funded by the staff of Duke University Medical Center.

J.B. Pracyk, Thomas C. Wall, J.Peter Longabaugh et al. · The American Journal of Cardiology · 1998 · 83 citations

Medicine, Cardiology, Surgery +12

Rac1 is required for cell proliferation and G2/M progression

Kimberly A. Moore, R Sethi, A. Masharn Doanes et al. · Biochemical Journal · 1997 · 75 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13