J. A. Whitsett

Targeted disruption of the surfactant protein B gene disrupts surfactant homeostasis, causing respiratory failure in newborn mice.

J. C. Clark, Susan E. Wert, Cindy J. Bachurski et al. · Proceedings of the National Academy of Sciences · 1995 · 640 citations

Life Sciences, Genetics, Molecular Genetics +8

Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis. A mouse model of progressive pulmonary fibrosis.

Yoshikazu Miyazaki, Kimi Araki, Christian Vesin et al. · Journal of Clinical Investigation · 1995 · 367 citations · Full text

Veterinary Medicine, Immunology, Pathobiology +16

Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity.

John A. Rankin, Dominic Picarella, Gregory P. Geba et al. · Proceedings of the National Academy of Sciences · 1996 · 345 citations

Life Sciences, Immunology, Pathology +16

Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF-deficient mice.

J.A. Huffman, William M. Hull, Glenn Dranoff et al. · Journal of Clinical Investigation · 1996 · 262 citations · Full text

Life Sciences, Cell Biology, Immunology +12

Airway epithelial cell expression of interleukin-6 in transgenic mice. Uncoupling of airway inflammation and bronchial hyperreactivity.

Bruno DiCosmo, Gregory P. Geba, Dominic Picarella et al. · Journal of Clinical Investigation · 1994 · 209 citations · Full text

Life Sciences, Immunology, Pathobiology +17