Adele M. Pauley

Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity

Riqiang Yan, Michael J. Bienkowski, Mary E. Shuck et al. · Nature · 1999 · 1.4K citations

Life Sciences, Biochemistry, Molecular Biology +14

The Notch Intracellular Domain Is Ubiquitinated and Negatively Regulated by the Mammalian Sel-10 Homolog

Camilla Öberg, Jinhe Li, Adele M. Pauley et al. · Journal of Biological Chemistry · 2001 · 413 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

SEL-10 Is an Inhibitor of Notch Signaling That Targets Notch for Ubiquitin-Mediated Protein Degradation

Guangyu Wu, Svetlana Lyapina, Indranil Das et al. · Molecular and Cellular Biology · 2001 · 332 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

SEL‐10 interacts with presenilin 1, facilitates its ubiquitination, and alters A‐beta peptide production

Jinhe Li, Adele M. Pauley, Rick L. Myers et al. · Journal of Neurochemistry · 2002 · 72 citations

Life Sciences, Genetics, Neuroscience +16

Direct interaction of soluble human recombinant tau protein with Aβ 1–42 results in tau aggregation and hyperphosphorylation by tau protein kinase II

Kenneth B. Rank, Adele M. Pauley, Keshab Bhattacharya et al. · FEBS Letters · 2002 · 67 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +14