Xiao‐Wu Chen

The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells

Shu-Feng Zhou, Jin‐Ping Li, Yinxue Yang et al. · Drug Design Development and Therapy · 2015 · 99 citations · Full text

Apoptosis, Cell Death, Human Breast Cancer +18

Curcumin enhances the effects of irinotecan on colorectal cancer cells through the generation of reactive oxygen species and activation of the endoplasmic reticulum stress pathway

Yanfeng Huang, Dajian Zhu, Xiao‐Wu Chen et al. · Oncotarget · 2017 · 96 citations · Full text

Curcumin attenuates resistance to irinotecan via induction of apoptosis of cancer stem cells in chemoresistant colon cancer cells

Pengfei Su, Yong Yang, Guoxin Wang et al. · International Journal of Oncology · 2018 · 92 citations · Full text

Chemoprevention Strategy, Cell Death, Cancer Biology +19

Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway

Shu‐Feng Zhou, Ningkui Niu, Zi-Li Wang et al. · Drug Design Development and Therapy · 2015 · 74 citations · Full text

Mitophagy, Chemoprevention Strategy, Apoptosis +20

Preclinical Evaluation of GS-9160, a Novel Inhibitor of Human Immunodeficiency Virus Type 1 Integrase

G.S. Jones, Fang Yu, Ameneh Zeynalzadegan et al. · Antimicrobial Agents and Chemotherapy · 2008 · 58 citations · Full text

Novel Inhibitor, Hiv-1 Integration, Medicine +15