Alan Ashworth

Identification of the breast cancer susceptibility gene BRCA2

Richard Wooster, Graham R. Bignell, Jonathan Lancaster et al. · Nature · 1995 · 3.7K citations

Medicine, Genetics, Molecular Genetics +9

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

Kyriaki Michailidou, Per Hall, Anna González‐Neira et al. · Nature Genetics · 2013 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

CYLD is a deubiquitinating enzyme that negatively regulates NF-κB activation by TNFR family members

Eirini Trompouki, Eudoxia Hatzivassiliou, Theodore Tsichritzis et al. · Nature · 2003 · 968 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells

Gemma Molyneux, Felipe C. Geyer, Fiona‐Ann Magnay et al. · Cell stem cell · 2010 · 808 citations · Full text

Medicine, Cancer Biology, Oncology +16

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

Dario R. Alessi, Mária Deák, Antonio Casamayor et al. · Current Biology · 1997 · 743 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14