Marcy E. MacDonald

Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection

Rong Liu, William A. Paxton, Sunny Choe et al. · Cell · 1996 · 3.1K citations · Full text

Life Sciences, Genetics, Infectious Diseases +13

Trinucleotide repeat length instability and age of onset in Huntington's disease

Mabel P. Duyao, C M Ambrose, Richard H. Myers et al. · Nature Genetics · 1993 · 1.1K citations

Medicine, Genetics, Molecular Genetics +12

Structure and expression of the Huntington's disease gene: Evidence against simple inactivation due to an expanded CAG repeat

Christine Ambrose, Mabel P. Duyao, Glenn Barnes et al. · Somatic Cell and Molecular Genetics · 1994 · 274 citations

Life Sciences, Genetics, Molecular Genetics +10

Permanent inactivation of Huntington's disease mutation by personalized allele-specific CRISPR/Cas9

Jun Wan Shin, Kyung‐Hee Kim, Michael J. Chao et al. · Human Molecular Genetics · 2016 · 273 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Reversal of a full-length mutant huntingtin neuronal cell phenotype by chemical inhibitors of polyglutamine-mediated aggregation

Jin Wang, Sílvia Ginés, Marcy E. MacDonald et al. · BMC Neuroscience · 2005 · 181 citations · Full text

Life Sciences, Neurology, Neuroscience +17