Leif Bertilsson

S-mephenytoin hydroxylation phenotypes in a Swedish population determined after coadministration with debrisoquin

Emílio J. Sanz, Tomás Villén, Christina Alm et al. · Clinical Pharmacology & Therapeutics · 1989 · 115 citations

Pharmacy, Pharmacokinetics, Pharmacology +11

S-mephenytoin hydroxylation phenotype and CYP2C19 genotype among Ethiopians

Eleni Aklillu, Fredrick Rodrigues, Leif Bertilsson et al. · Pharmacogenetics · 1996 · 90 citations

Medicine, Genetics, Pharmacology +17

Decreased capacity for debrisoquine metabolism among black Tanzanians: analyses of the CYP2D6 genotype and phenotype.

Agneta Wennerholm, Inger Johansson, Amos Massele et al. · PubMed · 1999 · 75 citations

Medicine, Genetics, Pharmacology +17

1- and 3-hydroxylations, in addition to 4-hydroxylation, of debrisoquine are catalyzed by cytochrome P450 2D6 in humans.

Birgit Eiermann, Per Olof Edlund, Agneta Tjernberg et al. · PubMed · 1998 · 26 citations

Medicine, Pharmacology, Toxicology +16

Enantioselective Determination of Mianserin and Its Desmethyl Metabolite in Plasma During Treatment of Depressed Japanese Patients

Gunnel Tybring, Koichi Otani, Sunao Kaneko et al. · Therapeutic Drug Monitoring · 1995 · 16 citations

Pharmacy, Pharmaceutical Analysis, Pharmacology +14