Kenneth J. Winters

Prasugrel versus Clopidogrel for Acute Coronary Syndromes without Revascularization

Matthew T. Roe, Paul W. Armstrong, Keith A.A. Fox et al. · New England Journal of Medicine · 2012 · 871 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +14

Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel

John T. Brandt, Sandra Close, Stephen J. Iturria et al. · Journal of Thrombosis and Haemostasis · 2007 · 730 citations

Medicine, Pharmacokinetics, Pharmacology +14

A comparison of prasugrel and clopidogrel loading doses on platelet function: magnitude of platelet inhibition is related to active metabolite formation

John T. Brandt, Christopher D. Payne, Stephen D. Wiviott et al. · American Heart Journal · 2006 · 570 citations

Medicine, Pharmacokinetics, Pharmacology +17

Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease

Tomas Jernberg, Christopher D. Payne, Kenneth J. Winters et al. · European Heart Journal · 2006 · 536 citations · Full text

Medicine, Cardiology, Pharmacology +17

Prasugrel achieves greater and faster P2Y12receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease

Lars Wallentin, Christoph Varenhorst, Stefan James et al. · European Heart Journal · 2007 · 455 citations · Full text

Medicine, Cardiology, Pharmacology +17