Gen Wang

AKT1/PKBα Kinase Is Frequently Elevated in Human Cancers and Its Constitutive Activation Is Required for Oncogenic Transformation in NIH3T3 Cells

Mei Sun, Gen Wang, June E. Paciga et al. · American Journal Of Pathology · 2001 · 452 citations · Full text

Medicine, Cancer Biology, Oncology +17

Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer

Zeng Qiang Yuan, Mei Sun, Richard I. Feldman et al. · Oncogene · 2000 · 387 citations

Life Sciences, Cell Biology, Oncology +16

A Poxvirus-Encoded Pyrin Domain Protein Interacts with ASC-1 to Inhibit Host Inflammatory and Apoptotic Responses to Infection

James B. Johnston, John W. Barrett, Steven H. Nazarian et al. · Immunity · 2005 · 227 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +16

Infection of human cancer cells with myxoma virus requires Akt activation via interaction with a viral ankyrin-repeat host range factor

Gen Wang, John W. Barrett, Marianne M. Stanford et al. · Proceedings of the National Academy of Sciences · 2006 · 192 citations · Full text

Veterinary Medicine, Cell Biology, Oncology +16

Myxoma Virus M11L Prevents Apoptosis through Constitutive Interaction with Bak

Gen Wang, John W. Barrett, Steven H. Nazarian et al. · Journal of Virology · 2004 · 90 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16