Guo Chen

Hypothalamus-habenula potentiation encodes chronic stress experience and drives depression onset

Zhiwei Zheng, Guo Chen, Min Li et al. · Neuron · 2022 · 143 citations

Medicine, Neurobiology, Neuroscience +16

Pathological oligodendrocyte precursor cells revealed in human schizophrenic brains and trigger schizophrenia-like behaviors and synaptic defects in genetic animal model

Guangdan Yu, Yixun Su, Guo Chen et al. · Molecular Psychiatry · 2022 · 62 citations · Full text

Medicine, Neuroscience, Psychiatry +17

Stress dynamically modulates neuronal autophagy to gate depression onset

Liang Yang, Guo Chen, Zhi-Wei Zheng et al. · Nature · 2025 · 47 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Inhibition of Syk promotes chemical reprogramming of fibroblasts via metabolic rewiring and H2S production

Weiyun Wang, Shaofang Ren, Yunkun Lu et al. · The EMBO Journal · 2021 · 36 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

A small population of stress-responsive neurons in the hypothalamus-habenula circuit mediates development of depression-like behavior in mice

Zhi-Wei Zheng, Yiqin Liu, Ruiqi Mu et al. · Neuron · 2024 · 27 citations · Full text

Veterinary Medicine, Neurobiology, Neuroscience +17