The ketone body metabolite β‐hydroxybutyrate induces an antidepression‐associated ramification of microglia via HDACs inhibition‐triggered Akt‐small RhoGTPase activation

Chao Huang, Peng Wang, Xing Xu, +10

Glia

Microglia Loss Contributes to the Development of Major Depression Induced by Different Types of Chronic Stresses

Lijuan Tong, Yu Gong, Peng Wang, +5

Neurochemical Research

InflammationChronic StressesPsychoneuroimmunologyStress HormonePsychiatry +13

Sodium butyrate triggers a functional elongation of microglial process via Akt-small RhoGTPase activation and HDACs inhibition

Peng Wang, Ya-Ru Zhang, Yu Gong, +8

Neurobiology of Disease

InflammationAnti-inflammatorySignal TransductionMolecular PhysiologyMedicine +12

Dynamic changes in hippocampal microglia contribute to depressive-like behavior induced by early social isolation

Yu Gong, Lijuan Tong, Rongrong Yang, +11

Neuropharmacology

Dynamic ChangesPsychoneuroimmunologyBrain FunctionPsychiatryHippocampal Microglia +10

Tauroursodeoxycholic acid produces antidepressant‐like effects in a chronic unpredictable stress model of depression via attenuation of neuroinflammation, oxido‐nitrosative stress, and endoplasmic reticulum stress

Xu Lu, Rongrong Yang, Jinlin Zhang, +6

Fundamental and Clinical Pharmacology

Psychotropic MedicationPsychopharmacologyEndoplasmic Reticulum StressTauroursodeoxycholic AcidSocial Sciences +19

WY-14643, a selective agonist of peroxisome proliferator-activated receptor-α, ameliorates lipopolysaccharide-induced depressive-like behaviors by preventing neuroinflammation and oxido-nitrosative stress in mice

Rongrong Yang, Peng Wang, Zhuo Chen, +4

Pharmacology Biochemistry and Behavior

Stress HormoneMedicineBehavioural PharmacologyPhysiologySelective Agonist +8

Vanillic Acid Alleviates Acute Myocardial Hypoxia/Reoxygenation Injury by Inhibiting Oxidative Stress

Xiuya Yao, Shoufeng Jiao, Mingming Qin, +3

Oxidative Medicine and Cellular Longevity

Farnesoid X Receptor-Mediated Cytoplasmic Translocation of CRTC2 Disrupts CREB-BDNF Signaling in Hippocampal CA1 and Leads to the Development of Depression-Like Behaviors in Mice

Wenfeng Hu, Jingjing Wu, Ting Ye, +7

The International Journal of Neuropsychopharmacology

Z-Guggulsterone Produces Antidepressant-Like Effects in Mice through Activation of the BDNF Signaling Pathway

Feng-Guo Liu, Wenfeng Hu, Jili Wang, +9

The International Journal of Neuropsychopharmacology

Z-guggulsterone negatively controls microglia-mediated neuroinflammation via blocking IκB-α–NF-κB signals

Chao Huang, Jili Wang, Xu Lu, +6

Neuroscience Letters

InflammationMolecular NeuroscienceMedicineBrain-immune InteractionSocial Sciences +6