Clonal heterogeneity in differentiation potential of immortalized human mesenchymal stem cells

Takeshi Okamoto, Tomoki Aoyama, Tomitaka Nakayama, +6

Biochemical and Biophysical Research Communications

Regenerative MedicineEmbryonic Stem CellClonal HeterogeneityDevelopmental BiologyMedicine +9

Expression of the p16INK4A Gene Is Associated Closely with Senescence of Human Mesenchymal Stem Cells and Is Potentially Silenced by DNA Methylation During In Vitro Expansion

Kotaro R. Shibata, Tomoki Aoyama, Yasuko Shima, +10

Stem Cells

Epigenetic ChangeGeneticsDna MethylationAdult Stem CellVitro Expansion +14

Increased MR signal intensity due to cervical myelopathy

Yasutaka Matsuda, Kazumi Miyazaki, Kenji Tada, +4

Journal of neurosurgery

Genome-wide analysis of gene expression in synovial sarcomas using a cDNA microarray.

Satoshi Nagayama, Toyomasa Katagiri, Tatsuhiko Tsunoda, +10

PubMed

EngineeringTumor InnervationImmunologyCdna MicroarrayPathology +18

MDM2 gene amplification in bone and soft‐tissue tumors: Association with tumor progression in differentiated adipose‐tissue tumors

Tomitaka Nakayama, Junya Toguchida, Bun‐Ichiro Wadayama, +3

International Journal of Cancer

Mesenchymal stem cells cultured under hypoxia escape from senescence via down-regulation of p16 and extracellular signal regulated kinase

Yonghui Jin, Tomohisa Kato, Moritoshi Furu, +8

Biochemical and Biophysical Research Communications

Mesenchymal Stem CellsExtracellular SignalCell SignalingMedicinePhysiology +10

Disruption of Fibroblast Growth Factor Signal Pathway Inhibits the Growth of Synovial Sarcomas: Potential Application of Signal Inhibitors to Molecular Target Therapy

Tatsuya Ishibe, Tomitaka Nakayama, Takeshi Okamoto, +9

Clinical Cancer Research

Characteristics of genomic breakpoints in TLS-CHOP translocations in liposarcomas suggest the involvement of Translin and topoisomerase II in the process of translocation

Hiroshi Kanoe, Tomitaka Nakayama, Taisuke Hosaka, +8

Oncogene

Tls-chop TranslocationsMolecular BiologyPathologyGenomic BreakpointsMolecular Pathology +3

FR901228 induces tumor regression associated with induction of Fas ligand and activation of Fas signaling in human osteosarcoma cells

Tsuyoshi Imai, Souichi Adachi, Koichi Nishijo, +9

Oncogene

Cancer ResearchHuman Osteosarcoma CellsSignal TransductionSignaling PathwayBone Morphogenic Protein +7

Amplification of the CDK4 gene in sarcomas: tumor specificity and relationship with the RB gene mutation.

Hiroshi Kanoe, Tomitaka Nakayama, Hiroshi Murakami, +7

PubMed

Mdm2 AmplificationCdk4 AmplificationTumoral PathologyMalignant DiseaseMedicine +13