Francis A. Ortega

Cell-Specific Cardiac Electrophysiology Models

Willemijn Groenendaal, Francis A. Ortega, Armen R. Kherlopian et al. · PLoS Computational Biology · 2015 · 118 citations · Full text

Medicine, Biophysics, Physiology +17

Global Optimization of Ventricular Myocyte Model to Multi-Variable Objective Improves Predictions of Drug-Induced Torsades de Pointes

Trine Krogh‐Madsen, Anna Jacobson, Francis A. Ortega et al. · Frontiers in Physiology · 2017 · 46 citations · Full text

Medicine, Cardiology, Pharmacology +17

Rapid Genetic Algorithm Optimization of a Mouse Computational Model: Benefits for Anthropomorphization of Neonatal Mouse Cardiomyocytes

Corina T. Bot, Armen R. Kherlopian, Francis A. Ortega et al. · Frontiers in Physiology · 2012 · 39 citations · Full text

Life Sciences, Bioengineering, Physiology +17

Differential roles of two delayed rectifier potassium currents in regulation of ventricular action potential duration and arrhythmia susceptibility

Ryan A. Devenyi, Francis A. Ortega, Willemijn Groenendaal et al. · The Journal of Physiology · 2016 · 38 citations · Full text

Medicine, Biophysics, Physiology +17

Voltage and Calcium Dynamics Both Underlie Cellular Alternans in Cardiac Myocytes

Willemijn Groenendaal, Francis A. Ortega, Trine Krogh‐Madsen et al. · Biophysical Journal · 2014 · 30 citations · Full text

Life Sciences, Biophysics, Cell Biology +12