John M. Littleton

Alcohol‐Induced Neurodegeneration: When, Where and Why?

Fulton T. Crews, Michael A. Collins, Cynthia A. Dlugos et al. · Alcoholism Clinical and Experimental Research · 2004 · 182 citations

Life Sciences, Neurobiology, Neuroscience +17

Acamprosate in alcohol dependence: how does it work?

John M. Littleton · Addiction · 1995 · 179 citations

Pharmacy, Pharmacology, Pharmacotherapy +11

Acamprosate inhibits the binding and neurotoxic effects of trans-ACPD, suggesting a novel site of action at metabotropic glutamate receptors.

Barton R. Harris, Mark Prendergast, D. Alex Gibson et al. · PubMed · 2002 · 125 citations

Life Sciences, Neuroscience, Pharmacology +17

Effects of dihydropyridine calcium channel antagonists in ethanol withdrawal; doses required, stereospecificity and actions of Bay K 8644

John M. Littleton, H.J. Little, Miles A. Whittington · Psychopharmacology · 1990 · 123 citations

Medicine, Pharmacology, Pharmacotherapy +15

Mechanism of Action of Acamprosate. Part II. Ethanol Dependence Modifies Effects of Acamprosate on NMDA Receptor Binding in Membranes from Rat Cerebral Cortex

Mona al Qatari, Ouahiba Bouchenafa, John M. Littleton · Alcoholism Clinical and Experimental Research · 1998 · 115 citations

Medicine, Neuroscience, Pharmacology +17