Simone Isbert

Metalloprotease Meprin β Generates Nontoxic N-terminal Amyloid Precursor Protein Fragments in Vivo

Tamara Jefferson, Mirsada Čaušević, Ulrich auf dem Keller et al. · Journal of Biological Chemistry · 2011 · 96 citations · Full text

Life Sciences, Biochemistry, Neuroscience +17

Generation of aggregation prone N-terminally truncated amyloid β peptides by meprin β depends on the sequence specificity at the cleavage site

Caroline Schönherr, Jessica Bien, Simone Isbert et al. · Molecular Neurodegeneration · 2016 · 72 citations · Full text

Life Sciences, Biochemistry, Neuroscience +17

Increased AICD generation does not result in increased nuclear translocation or activation of target gene transcription

Elaine Waldron, Simone Isbert, Andreas Kern et al. · Experimental Cell Research · 2008 · 44 citations

Life Sciences, Genetics, Molecular Biology +9

APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms

Simone Isbert, Katja Wagner, Simone Eggert et al. · Cellular and Molecular Life Sciences · 2011 · 42 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Inactivation of the proximal NPXY motif impairs early steps in LRP1 biosynthesis

Sara Reekmans, Thorsten Pflanzner, Philip L.S.M. Gordts et al. · Cellular and Molecular Life Sciences · 2009 · 33 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +7