Laurent Degos

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

Hugues de Thé, Catherine Lavau, Agnès Marchio et al. · Cell · 1991 · 1.4K citations

Life Sciences, Molecular Biology, Molecular Genetics +10

The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor α gene to a novel transcribed locus

Hugues de Thé, Christine Chomienne, Michel Lanotte et al. · Nature · 1990 · 1.4K citations

Life Sciences, Genetics, Molecular Genetics +13

A Randomized Comparison of All Transretinoic Acid (ATRA) Followed by Chemotherapy and ATRA Plus Chemotherapy and the Role of Maintenance Therapy in Newly Diagnosed Acute Promyelocytic Leukemia

Pierre Fenaux, Claude Chastang, Sylvie Chevret et al. · Blood · 1999 · 745 citations

Medicine, Hematology, Oncology +12

Arsenic-induced PML targeting onto nuclear bodies: Implications for the treatment of acute promyelocytic leukemia

Jun Zhu, Marcel Koken, Frédérique Quignon et al. · Proceedings of the National Academy of Sciences · 1997 · 437 citations

Life Sciences, Cell Biology, Molecular Biology +17

A Controlled Study of Recombinant Human Granulocyte Colony-Stimulating Factor in Elderly Patients after Treatment for Acute Myelogenous Leukemia

Hervé Dombret, Claude Chastang, Pierre Fenaux et al. · New England Journal of Medicine · 1995 · 312 citations · Full text

Medicine, Hematology, Oncology +16