Paul E. Fraser

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

Robin Sherrington, Ekaterina Rogaeva, Georges Lévesque et al. · Nature · 1995 · 2.1K citations

Life Sciences, Genetics, Molecular Genetics +14

Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

Christopher Janus, Jacqueline Pearson, JoAnne McLaurin et al. · Nature · 2000 · 1.4K citations

Life Sciences, Neurobiology, Neuroscience +14

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

Ekaterina Rogaeva, Yan Meng, Joseph H. Lee et al. · Nature Genetics · 2007 · 1.2K citations · Full text

Life Sciences, Neurobiology, Neuroscience +12

Early-onset Amyloid Deposition and Cognitive Deficits in Transgenic Mice Expressing a Double Mutant Form of Amyloid Precursor Protein 695

M. Azhar Chishti, Dun-Shen Yang, Christopher Janus et al. · Journal of Biological Chemistry · 2001 · 954 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions

Seema Qamar, Guo-Zhen Wang, Suzanne J. Randle et al. · Cell · 2018 · 944 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17