The pathobiology of blast injuries and blast-induced neurotrauma as identified using a new experimental model of injury in mice

Ibolja Černak, Andrew C. Merkle, Vassilis E. Koliatsos, +7

Neurobiology of Disease

InflammationTraumatic Brain InjuryBlast-induced NeurotraumaNew Experimental ModelClinical Injury +13

Human Neural Stem Cell Grafts Ameliorate Motor Neuron Disease in SOD-1 Transgenic Rats

Leyan Xu, Jun Yan, David Chen, +5

Transplantation

A Mouse Model of Blast Injury to Brain: Initial Pathological, Neuropathological, and Behavioral Characterization

Vassilis E. Koliatsos, Ibolja Černak, Leyan Xu, +8

Journal of Neuropathology & Experimental Neurology

Acute Lung InjuryTraumatic Brain InjuryNeuroinflammationBehavioral CharacterizationNeuroregeneration +23

Extensive Neuronal Differentiation of Human Neural Stem Cell Grafts in Adult Rat Spinal Cord

Jun Yan, Leyan Xu, Annie M. Welsh, +4

PLoS Medicine

Human neural stem cell grafts in the spinal cord of SOD1 transgenic rats: Differentiation and structural integration into the segmental motor circuitry

Leyan Xu, David K. Ryugo, Tan Pongstaporn, +2

The Journal of Comparative Neurology

Segmental Motor CircuitryCerebral OrganoidCellular NeurobiologyNeuroregenerationMotor Circuitry +20

Repetitive mild traumatic brain injury with impact acceleration in the mouse: Multifocal axonopathy, neuroinflammation, and neurodegeneration in the visual system

Leyan Xu, Judy V. Nguyen, Mohamed Lehar, +7

Experimental Neurology

Traumatic Brain InjuryNeuroregenerationNeuroanatomyNeurological InjuryMultifocal Axonopathy +9

Combined Immunosuppressive Agents or CD4 Antibodies Prolong Survival of Human Neural Stem Cell Grafts and Improve Disease Outcomes in Amyotrophic Lateral Sclerosis Transgenic Mice

Jun Yan, Leyan Xu, Annie M. Welsh, +4

Stem Cells

Cell TherapyMotor Neuron DiseaseImmunologyImmunotherapyImprove Disease Outcomes +18

Nanofiber Matrices Promote the Neuronal Differentiation of Human Embryonic Stem Cell-Derived Neural Precursors <i>In Vitro</i>

Vasiliki Mahairaki, Shawn Lim, Gregory T. Christopherson, +5

Tissue Engineering Part A

Tissue EngineeringEngineeringBiomaterials DesignBiofabricationNeuronal Differentiation +20

DISC1 immunoreactivity at the light and ultrastructural level in the human neocortex

Brian Kirkpatrick, Leyan Xu, Nicola G. Cascella, +3

The Journal of Comparative Neurology

Dual transplantation of human neural stem cells into cervical and lumbar cord ameliorates motor neuron disease in SOD1 transgenic rats

Leyan Xu, Peilin Shen, Thomas G. Hazel, +2

Neuroscience Letters

Neurodegenerative DiseasesNeuroregenerationSpinal Cord InjuryAmyotrophic Lateral SclerosisMotor Neuron Disease +11