Bing‐Yan Zhu

Discovery of a Potent, Selective, and Orally Available Class I Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor (GDC-0980) for the Treatment of Cancer

Daniel P. Sutherlin, Linda Bao, Megan Berry et al. · Journal of Medicinal Chemistry · 2011 · 217 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Packing and hydrophobicity effects on protein folding and stability: Effects of <i>β</i>‐branched amino acids, valine and isoleucine, on the formation and stability of two‐stranded <i>α</i>‐helical coiled coils/leucine zippers

Bing‐Yan Zhu, Cyril M. Kay, Robert S. Hodges · Protein Science · 1993 · 186 citations · Full text

Life Sciences, Biochemistry, Biophysics +17

The two‐stranded α‐helical coiled‐coil is an ideal model for studying protein stability and subunit interactions

Nian Zhou, Bing‐Yan Zhu, Cyril M. Kay et al. · Biopolymers · 1992 · 134 citations

Life Sciences, Biochemistry, Molecular Biology +15

Organocerium compounds in synthesis

Hsing‐Jang Liu, Kak‐Shan Shia, Xiao Shang et al. · Tetrahedron · 1999 · 134 citations

Natural Sciences, Biochemistry, Chemistry +5

Discovery of (Thienopyrimidin-2-yl)aminopyrimidines as Potent, Selective, and Orally Available Pan-PI3-Kinase and Dual Pan-PI3-Kinase/mTOR Inhibitors for the Treatment of Cancer

Daniel P. Sutherlin, Deepak Sampath, Megan Berry et al. · Journal of Medicinal Chemistry · 2010 · 131 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17